1.What the tool can do for you?

This tool focuses on exploring correlation between probesets in gene expression data and compare with clinical data available.

Original paper: Horvath et al, BMC Bioinformatics 2008, 9:559 doi:10.1186/1471-2105-9-559 'WGCNA: an R package for weighted correlation network analysis'

The following image is from: Jiang et al, BMC Genomics 2014 15:756 doi:10.1186/1471-2164-15-756, 'Transcriptional profiles of bovine in vivo pre-implantation development'

2.How to get the tool

Please download here the source package: link

3.Learn how to use the tool

Please download here the package installation guide: link

WGCNA tutorials (in R): http://labs.genetics.ucla.edu/horvath/CoexpressionNetwork/Rpackages/WGCNA/Tutorials/

4.How to get Involved

Please contact bdemeulder@eisbm.org if you want to participate the development of the application.

5.Acknowledgements

We would like to acknowledge the authors of the following R packages (WGCNA, rmarkdown, plotly, shiny, stringr, DT, NetworkD3, gplots, impute) needed for the main app, the author of the radiant R package for the inspiration for the save/load functionality and the authors of the paper “Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight”, PLoS Genetics, 2006, for publishing the data used as demo datasets.